Palmitoylethanolamide (PEA) is a long chain fatty acid naturally produced by the body but also found in foods such as egg yolk, soy and sunflower oils. This molecule, researched for its unique and varied health benefits for eighty years, is now receiving attention because of its crucial role in the endocannabinoid system (ECS). The ECS is a lipid communication network with critical physiological functions. It is a signaling network that communicates with other systems throughout the body, helping to regulate them. PEA is an endocannabinoid produced locally by the cells, and it accumulates in tissues following any injury, physical stress or pain.By inhibiting the activation of mast cells that cause additional inflammation (such as the release of histamine), PEA acts as a potent anti-inflammatory agent. This unique molecule has other direct and indirect mechanisms of action. The PEA molecule has been clinically demonstrated to relieve chronic pain and is well tolerated for many populations.AOR AdvantageAOR is leading the way by transforming the impressive and evolving research on PEA’s positive effects within the human endocannabinoid system, bringing you a safe and therapeutic formulation to combat chronic pain and systemic inflammation. The PEA in AOR’s P.E.A.k Activate is produced in Italy and originally extracted from environmentally sustainable Malaysian palm oil that is purified and responsibly processed for optimal bioavailability.