The more absorbable form of magnesium, bisglycinate, has replaced the magnesium oxide due to its superior absorption. Silica-rich horsetail promotes the strength and elasticity of connective tissue. Curcumin 95% curcuminoids is among the new ingredients in Strong Bones. Lutein extract supports levels of this carotenoid, which have been shown in studies to be deficient in women with several forms of osteoporosis. Grape seed extract, 80% oligomeric proanthocyanidins, has been shown to enhance bone density in animal trials. Green tea, 75% epigallocatechin gallate — According to studies out of Hong Kong, green-tea EGCG boosted the activity of a key enzyme that promotes bone growth by up to 79%. EGCG also significantly boosted levels of bone mineralization in the cells, which strengthens bones. Scientists also showed that high concentrations of EGCG blocked the activity of a type of cell (osteoclast) that breaks down or weakens bones. Lycopene, a phytochemical found in tomatoes, protects bone-producing cells from oxidative stress. Studies in both the US and the Netherlands have shown folic acid supplementation helps prevent bone fractures in the elderly. The coenzyme form of vitamin B12, methylcobalamin, completes the formula, as research at Tufts University have identified methylcobalamin as a modifiable risk factor in bone mineral density research.